Histamine Induces Egr-1 Expression in Human Aortic Endothelial Cells via the H1 Receptor-mediated Protein Kinase Cδ-dependent ERK Activation Pathway

Histamine, a potent inflammatory mediator, has multiple effects on the pathogenesis of atherosclerosis. This study investigates the effect of histamine on the expression of early growth response factor 1 (Egr-1), a master transcription factor that regulates the expression of an array of atherogenic...

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Veröffentlicht in:The Journal of biological chemistry 2008-10, Vol.283 (40), p.26928
Hauptverfasser: Feng Hao, Mingqi Tan, Xuemin Xu, Mei-Zhen Cui
Format: Artikel
Sprache:eng
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