N-type Inactivation of the Potassium Channel KcsA by the Shaker B “Ball” Peptide

The effects of the inactivating peptide from the eukaryotic Shaker BK + channel (the ShB peptide) on the prokaryotic KcsA channel have been studied using patch clamp methods. The data show that the peptide induces rapid, N-type inactivation in KcsA through a process that includes functional uncoupli...

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Veröffentlicht in:The Journal of biological chemistry 2008-06, Vol.283 (26), p.18076
Hauptverfasser: M. Luisa Molina, Francisco N. Barrera, José A. Encinar, M. Lourdes Renart, Asia M. Fernández, José A. Poveda, Jorge Santoro, Marta Bruix, Francisco Gavilanes, Gregorio Fernández-Ballester, José L. Neira, José M. González-Ros
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Sprache:eng
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