Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLCβ3 to Regulate Intracellular Free Calcium

Studies in fibroblasts, neurons, and platelets have demonstrated the integration of signals from different G protein-coupled receptors (GPCRs) in raising intracellular free Ca 2+ . To study signal integration in macrophages, we screened RAW264.7 cells and bone marrow-derived macrophages (BMDM) for t...

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Veröffentlicht in:The Journal of biological chemistry 2008-06, Vol.283 (25), p.17351
Hauptverfasser: Tamara I. A. Roach, Robert A. Rebres, Iain D. C. Fraser, Dianne L. DeCamp, Keng-Mean Lin, Paul C. Sternweis, Mel I. Simon, William E. Seaman
Format: Artikel
Sprache:eng
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