Differential Modulation of 3T3-L1 Adipogenesis Mediated by 11β-Hydroxysteroid Dehydrogenase-1 Levels

The localized activation of circulating glucocorticoids in vivo by the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) plays a critical role in the development of the metabolic syndrome. However, the precise contribution of 11β-HSD1 in the initiation of adipogenesis by inactive glucocor...

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Veröffentlicht in:The Journal of biological chemistry 2007-04, Vol.282 (15), p.11038
Hauptverfasser: Jaime Kim, Karla A. Temple, Sara A. Jones, Kimberly N. Meredith, Juliana L. Basko, Matthew J. Brady
Format: Artikel
Sprache:eng
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