Promoter Organization of the Interferon-A Genes Differentially Affects Virus-induced Expression and Responsiveness to TBK1 and IKKϵ

Virus-induced expression of interferon (IFN)-A genes is regulated by two members of the IFN regulatory factor (IRF) family, IRF-3 and IRF-7, which are activated by phosphorylation during viral infection by the IKK-related serine/threonine kinases TBK1 and IκB kinase ϵ (IKKϵ). In this study, we de...

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Veröffentlicht in:	The Journal of biological chemistry 2006-02, Vol.281 (8), p.4856
Hauptverfasser:	Ahmet Civas, Pierre Génin, Pierre Morin, Rongtuan Lin, John Hiscott
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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