Negative Modulation of RXRα Transcriptional Activity by Small Ubiquitin-related Modifier (SUMO) Modification and Its Reversal by SUMO-specific Protease SUSP1

Retinoid X receptor α (RXRα) belongs to a family of ligand-activated transcription factors that regulate many aspects of metazoan life. Here we demonstrate that RXRα is a target substrate of a small ubiquitin-related modifier (SUMO)-specific protease, SUSP1, which is capable of controlling the tr...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 2006-10, Vol.281 (41), p.30669
Hauptverfasser:	Soo Joon Choi, Sung Soo Chung, Eun Jung Rho, Hyung Woo Lee, Moon Hee Lee, Hueng-Sik Choi, Jae Hong Seol, Sung Hee Baek, Ok Sun Bang, Chin Ha Chung
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!