β-Adrenergic Receptor Stimulation and Adenoviral Overexpression of Superoxide Dismutase Prevent the Hypoxia-mediated Decrease in Na,K-ATPase and Alveolar Fluid Reabsorption

Hypoxia has been shown to cause lung edema and impair lung edema clearance. In the present study, we exposed isolated rat lungs to p O 2 = 40 mm Hg for 60 min or rats to 8% O 2 for up to 24 h and then measured changes in alveolar fluid reabsorption (AFR) and Na,K-ATPase function. Low levels of oxyge...

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Veröffentlicht in:	The Journal of biological chemistry 2006-07, Vol.281 (29), p.19892
Hauptverfasser:	Juan Litvan, Arturo Briva, Mindy S. Wilson, G. R. Scott Budinger, Jacob Iasha Sznajder, Karen M. Ridge
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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