Gβγ Binds Histone Deacetylase 5 (HDAC5) and Inhibits Its Transcriptional Co-repression Activity
In a yeast two-hybrid screen designed to identify novel effectors of the Gβγ subunit of heterotrimeric G proteins, we found that Gβγ binds to histone deacetylase 5 (HDAC5), an enzyme involved in a pathway not previously recognized to be directly impacted by G proteins. Formation of the Gβ 1 γ...
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| Veröffentlicht in: | The Journal of biological chemistry 2005-12, Vol.280 (50), p.41769 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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