A Role for the Distal Carboxyl Tails in Generating the Novel Pharmacology and G Protein Activation Profile of μ and δ Opioid Receptor Hetero-oligomers

Opioid receptor pharmacology in vivo has predicted a greater number of receptor subtypes than explained by the profiles of the three cloned opioid receptors, and the functional dependence of the receptors on each other shown in gene-deleted animal models remains unexplained. One mechanism for such f...

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Veröffentlicht in:The Journal of biological chemistry 2005-11, Vol.280 (46), p.38478
Hauptverfasser: Theresa Fan, George Varghese, Tuan Nguyen, Roderick Tse, Brian F. O'Dowd, Susan R. George
Format: Artikel
Sprache:eng
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