Distinct Role of Calmodulin and Calmodulin-dependent Protein Kinase-II in Lipopolysaccharide and Tumor Necrosis Factor-α-mediated Suppression of Apoptosis and Antiapoptotic c-IAP2 Gene Expression in Human Monocytic Cells

Exposure of phagocytic cells to bacterial endotoxin (lipopolysaccharide; LPS) or inflammatory cytokines confers antiapoptotic survival signals; however, in the absence of the appropriate stimulus, monocytes are programmed to undergo apoptosis. Macrophage survival may thus influence inflammatory and...

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Veröffentlicht in:The Journal of biological chemistry 2005-11, Vol.280 (45), p.37536
Hauptverfasser: Sasmita Mishra, Jyoti P. Mishra, Katrina Gee, Dan C. McManus, Eric C. LaCasse, Ashok Kumar
Format: Artikel
Sprache:eng
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