X-ray Structure of Human Acid-β-Glucosidase Covalently Bound to Conduritol-B-Epoxide

Gaucher disease is an inherited metabolic disorder caused by mutations in the lysosomal enzyme acid-β-glucosidase (GlcCerase). We recently determined the x-ray structure of GlcCerase to 2.0 Å resolution (Dvir, H., Harel, M., McCarthy, A. A., Toker, L., Silman, I., Futerman, A. H., and Sussman, J....

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Veröffentlicht in:	The Journal of biological chemistry 2005-06, Vol.280 (25), p.23815
Hauptverfasser:	Lakshmanane Premkumar, Anu R. Sawkar, Swetlana Boldin-Adamsky, Lilly Toker, Israel Silman, Jeffery W. Kelly, Anthony H. Futerman, Joel L. Sussman
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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