Regulation of Outside-in Signaling in Platelets by Integrin-associated Protein Kinase CÎ

Studies with inhibitors have implicated protein kinase C (PKC) in the adhesive functions of integrin α IIb β 3 in platelets, but the responsible PKC isoforms and mechanisms are unknown. α IIb β 3 interacts directly with tyrosine kinases c-Src and Syk. Therefore, we asked whether α IIb β 3 migh...

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Veröffentlicht in:	The Journal of biological chemistry 2005-01, Vol.280 (1), p.644
Hauptverfasser:	Charito S. Buensuceso, Achim Obergfell, Alessandra Soriani, Koji Eto, William B. Kiosses, Elena G. Arias-Salgado, Toshiaki Kawakami, Sanford J. Shattil
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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