Expression of NAG-1, a Transforming Growth Factor-β Superfamily Member, by Troglitazone Requires the Early Growth Response Gene EGR-1
Troglitazone (TGZ) and 15-deoxy-Π12,14 -prostaglandin J 2 (PGJ 2 ) are peroxisome proliferator-activated receptor-γ (PPARγ) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. Although these compounds bind to PPARγ transcription factors as agonists, emerging ev...
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Veröffentlicht in: | The Journal of biological chemistry 2004-02, Vol.279 (8), p.6883 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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