Expression of NAG-1, a Transforming Growth Factor-β Superfamily Member, by Troglitazone Requires the Early Growth Response Gene EGR-1

Troglitazone (TGZ) and 15-deoxy-Δ 12,14 -prostaglandin J 2 (PGJ 2 ) are peroxisome proliferator-activated receptor-γ (PPARγ) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. Although these compounds bind to PPARγ transcription factors as agonists, emerging ev...

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Veröffentlicht in:The Journal of biological chemistry 2004-02, Vol.279 (8), p.6883
Hauptverfasser: Seung Joon Baek, Jong-Sik Kim, Jennifer B. Nixon, Richard P. DiAugustine, Thomas E. Eling
Format: Artikel
Sprache:eng
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