Eosinophil Peroxidase-derived Reactive Brominating Species Target the Vinyl Ether Bond of Plasmalogens Generating a Novel Chemoattractant, α-Bromo Fatty Aldehyde

Plasmalogens are a subclass of glycerophospholipids that are enriched in the plasma membrane of many mammalian cells. The vinyl ether bond of plasmalogens renders them susceptible to oxidation. Accordingly, it was hypothesized that reactive brominating species, a unique oxidant formed at the sites o...

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Veröffentlicht in:The Journal of biological chemistry 2003-03, Vol.278 (11), p.8942
Hauptverfasser: Carolyn J. Albert, Arun K. Thukkani, Rita M. Heuertz, Arne Slungaard, Stanley L. Hazen, David A. Ford
Format: Artikel
Sprache:eng
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