New Class of Inhibitors of Amyloid-β Fibril Formation

The amyloid hypothesis suggests that the process of amyloid-β protein (Aβ) fibrillogenesis is responsible for triggering a cascade of physiological events that contribute directly to the initiation and progression of Alzheimer's disease. Consequently, preventing this process might provide a v...

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Veröffentlicht in:The Journal of biological chemistry 2002-11, Vol.277 (45), p.42881
Hauptverfasser: Hilal A. Lashuel, Dean M. Hartley, David Balakhaneh, Aneel Aggarwal, Saul Teichberg, David J. E. Callaway
Format: Artikel
Sprache:eng
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