Tapasin Interacts with the Membrane-spanning Domains of Both TAP Subunits and Enhances the Structural Stability of TAP1·TAP2 Complexes

The transporter associated with antigen processing (TAP) proteins are involved in transport of peptides from the cytosol into the endoplasmic reticulum. Two subunits, TAP1 and TAP2, are necessary and sufficient for peptide binding and peptide translocation across the endoplasmic reticulum membrane....

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Veröffentlicht in:The Journal of biological chemistry 2002-11, Vol.277 (44), p.41786
Hauptverfasser: Gayatri Raghuraman, Philip Edward Lapinski, Malini Raghavan
Format: Artikel
Sprache:eng
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