Ca2+-dependent Dephosphorylation of Kinesin Heavy Chain on β-Granules in Pancreatic β-Cells

The specific biochemical steps required for glucose-regulated insulin exocytosis from β-cells are not well defined. Elevation of glucose leads to increases in cytosolic [Ca 2+ ] i and biphasic release of insulin from both a readily releasable and a storage pool of β-granules. The effect of elevate...

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Veröffentlicht in:The Journal of biological chemistry 2002-07, Vol.277 (27), p.24232
Hauptverfasser: Matthew J. Donelan, Gerardo Morfini, Richard Julyan, Scott Sommers, Lori Hays, Hiroshi Kajio, Isabelle Briaud, Richard A. Easom, Jeffery D. Molkentin, Scott T. Brady, Christopher J. Rhodes
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Sprache:eng
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