Kaurane Diterpene, Kamebakaurin, Inhibits NF-κB by Directly Targeting the DNA-binding Activity of p50 and Blocks the Expression of Antiapoptotic NF-κB Target Genes

Kaurane diterpenes have been identified from numerous medicinal plants, which have been used for treatment of inflammation and cancer, however, their molecular mechanism of action remains unclear. We have previously shown that kamebakaurin and other three kaurane diterpenes selectively inhibit activ...

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Veröffentlicht in:	The Journal of biological chemistry 2002-05, Vol.277 (21), p.18411
Hauptverfasser:	Jeong-Hyung Lee, Tae Hyeon Koo, Bang Yeon Hwang, Jung Joon Lee
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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