Positive and Negative Effects of the Major Mammalian Messenger Ribonucleoprotein p50 on Binding of 40 S Ribosomal Subunits to the Initiation Codon of β-Globin mRNA

p50, the major core protein bound to mammalian mRNAs, has been reported to stimulate translation at low p50/mRNA ratios and inhibit translation at high p50/mRNA ratios. This study aims to address the molecular mechanisms underlying these phenomena using the in vitro assembly of 48 S preinitiation co...

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Veröffentlicht in:	The Journal of biological chemistry 2002-05, Vol.277 (18), p.15445
Hauptverfasser:	Andrey V. Pisarev, Maksim A. Skabkin, Adri A. Thomas, William C. Merrick, Lev P. Ovchinnikov, Ivan N. Shatsky
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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