Involvement of the Nucleotide Excision Repair Protein UvrA in Instability of CAG·CTG Repeat Sequences in Escherichia coli

Several human genetic diseases have been associated with the genetic instability, specifically expansion, of trinucleotide repeat sequences such as (CTG) n ·(CAG) n . Molecular models of repeat instability imply replication slippage and the formation of loops and imperfect hairpins in single strand...

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Veröffentlicht in:	The Journal of biological chemistry 2001-08, Vol.276 (33), p.30878
Hauptverfasser:	Elena A. Oussatcheva, Vera I. Hashem, Yue Zou, Richard R. Sinden, Vladimir N. Potaman
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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