Loss of IκB-β Is Associated with Prolonged NF-κB Activity in Human Glial Cells

Nuclear factor-κB (NF-κB) is an inducible transcription factor central in the regulation of expression of a wide variety of genes and synthesis of several proteins involved in the generation of the immune response and inflammatory processes. In resting cells, NF-κB is maintained in an inactive st...

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Veröffentlicht in:The Journal of biological chemistry 2000-12, Vol.275 (51), p.39996
Hauptverfasser: Emer Bourke, Eugene J. Kennedy, Paul N. Moynagh
Format: Artikel
Sprache:eng
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