One or More Labile Proteins Regulate the Stability of Chimeric mRNAs Containing the 3′-Untranslated Region of Cholesterol-7α-hydroxylase mRNA

Multiple AUUUA elements similar to those that regulate the degradation of several different mRNAs are conserved in the 3′-untranslated region (3′-UTR) of cholesterol-7α-hydroxylase (CYP7A1) mRNAs from several species. We examined if stabilization of mRNA decay could account for the >20-fold...

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Veröffentlicht in:The Journal of biological chemistry 2000-06, Vol.275 (26), p.19985
Hauptverfasser: Daniel M. Baker, Shui-Long Wang, David J. Bell, Christian A. Drevon, Roger A. Davis
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Sprache:eng
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