An Atypical Form of αB-crystallin Is Present in High Concentration in Some Human Cataractous Lenses

Two unique polypeptides, 22.4 and 16.4 kDa, were prominent in some human cataracts. Both proteins were identified as modified forms of the small heat shock protein, αB-crystallin. The concentration of total αB-crystallin in most of these cataracts was significantly increased. The 22.4-kDa protein...

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Veröffentlicht in:The Journal of biological chemistry 1999-11, Vol.274 (45), p.32287
Hauptverfasser: Jose Jimenez-Asensio, Christine M. Colvis, Jeffrey A. Kowalak, Yvonne Duglas-Tabor, Manuel B. Datiles, Maria Moroni, Umberto Mura, Ch. Mohan Rao, Dorairajan Balasubramanian, Alireza Janjani, Donita Garland
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Sprache:eng
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