Platelet-derived Growth Factor Stimulates Protein Kinase D through the Activation of Phospholipase Cγ and Protein Kinase C

Platelet-derived growth factor (PDGF) stimulates protein kinase D (PKD) in a time- and dose-dependent manner. We have used a series of PDGF receptor mutants that display a selective impairment of the binding of SH2-containing proteins (GTPase-activating protein, SHP-2, phospholipase Cγ (PLCγ), or...

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Veröffentlicht in:The Journal of biological chemistry 1998-03, Vol.273 (12), p.7038
Hauptverfasser: Johan Van Lint, Youping Ni, Mindaugas Valius, Wilfried Merlevede, Jackie R. Vandenheede
Format: Artikel
Sprache:eng
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