Sterically Stabilized pH-sensitive Liposomes

Liposomes that destabilize at mildly acidic pH are efficient tools for delivering water-soluble drugs into the cell cytoplasm. However, their use in vivo is limited because of their rapid uptake from circulation by the reticuloendothelial system. Lipid-anchored polyethylene glycol (PEG-PE) prolongs...

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Veröffentlicht in:	The Journal of biological chemistry 1997-01, Vol.272 (4), p.2382
Hauptverfasser:	Vladimir A. Slepushkin, Sérgio Simões, Paul Dazin, Mary S. Newman, Luke S. Guo, Maria C. Pedroso de Lima, Nejat DüzgüneÅ
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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