c-Myb trans-Activates the Human DNA Topoisomerase IIα Gene Promoter
DNA topoisomerase IIα (topo IIα) is an essential proliferation-dependent nuclear enzyme which has been exploited as an anti-tumor drug target. Since the proliferative status of human leukemia cells is associated with expression of the c- myb proto-oncogene, c-Myb was investigated as a trans -activ...
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Veröffentlicht in: | The Journal of biological chemistry 1997-03, Vol.272 (10), p.6278 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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