Evidence for α-Helical Conformation of an Essential N-terminal Region in the Human Bcl2 Protein

A region occupying approximately 24 amino acids near the N terminus of human Bcl2 is essential for this cytoplasmic membrane protein's ability to inhibit apoptosis. Systematic mutagenesis of this N-terminal region indicates that only five hydrophobic and aromatic residues within it are specific...

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Veröffentlicht in:	The Journal of biological chemistry 1996-09, Vol.271 (38), p.23284
Hauptverfasser:	Lillian C. Lee, John J. Hunter, Anwer Mujeeb, Christoph Turck, Tristram G. Parslow
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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