Morphology and Toxicity of Aβ-(1-42) Dimer Derived from Neuritic and Vascular Amyloid Deposits of Alzheimer's Disease

In the course of analyzing the chemical composition of Alzheimer's disease neuritic and vascular amyloid, we have purified stable dimeric and trimeric components of Aβ peptides. These peptides (molecular mass 9.0 and 13.5 kDa) were separated by size exclusion chromatography in the presence of...

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Veröffentlicht in:The Journal of biological chemistry 1996-08, Vol.271 (34), p.20631
Hauptverfasser: Alex E. Roher, Michael O. Chaney, Yu-Min Kuo, Scott D. Webster, W. Blaine Stine, Lanny J. Haverkamp, Amina S. Woods, Robert J. Cotter, James M. Tuohy, Grant A. Krafft, Barry S. Bonnell, Mark R. Emmerling
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Sprache:eng
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