Ca Mobilizing Action of Sphingosine in Jurkat Human Leukemia T Cells

Effects of sphingosine on Ca mobilization in the human Jurkat T cell line were examined. Sphingosine increased the cytoplasmic Ca concentration ([Ca ] ) in a dose-dependent manner with an ED of around 8 μM. Sphingosine and OKT3, a CD3 monoclonal antibody, transiently increased [Ca ] , which decline...

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Veröffentlicht in:	The Journal of biological chemistry 1996-05, Vol.271 (19), p.11148
Hauptverfasser:	Shoji Sakano, Haruo Takemura, Keiko Yamada, Kenshi Imoto, Masamitsu Kaneko, Hideyo Ohshika
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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