Aggregation of Secreted Amyloid -Protein into Sodium Dodecyl Sulfate-stable Oligomers in Cell Culture

Filamentous aggregates of the 40-42-residue amyloid β-protein (Aβ) accumulate progressively in the limbic and cerebral cortex in Alzheimer's disease, where they are intimately associated with neuronal and glial cytopathology. Attempts to model this cytotoxicity in vitro using synthetic peptid...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 1995-04, Vol.270 (16), p.9564
Hauptverfasser:	Marcia B. Podlisny, Beth L. Ostaszewski, Sharon L. Squazzo, Edward H. Koo, Russell E. Rydell, David B. Teplow, Dennis J. Selkoe
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!