Nitric Oxide-stimulated Guanine Nucleotide Exchange on p21

The protooncogene p21 , a monomeric G protein family member, plays a critical role in converting extracellular signals into intracellular biochemical events. Here, we report that nitric oxide (NO) activates p21 in human T cells as evidenced by an increase in GTP-bound p21 . In vitro studies using pu...

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Veröffentlicht in:	The Journal of biological chemistry 1995-03, Vol.270 (13), p.7017
Hauptverfasser:	Harry M. Lander, Jason S. Ogiste, S. Frieda A. Pearce, Roberto Levi, Abraham Novogrodsky
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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