Isolation and Characterization of C-4 Methyl Intermediates in Cholesterol Biosynthesis after Treatment of Rat Liver in Vitro with Cholestan-3β,5α,6β-triol
We have studied the effect in vitro of cholestan-3β,5α, 6β-triol upon the conversion of tritium-labeled mavalonic acid to cholesterol. An in vitro system is described which is capable of net sterol synthesis in milligram quantities. Thus it is possible to characterize accumulating intermediates b...
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| Veröffentlicht in: | The Journal of biological chemistry 1971-05, Vol.246 (10), p.3168 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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