The Phenylmethylthiazolylthiourea Nonnucleoside Reverse Transcriptase (RT) Inhibitor MSK-076 Selects for a Resistance Mutation in the Active Site of Human Immunodeficiency Virus Type 2 RT
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| Veröffentlicht in: | Journal of Virology 2004-07, Vol.78 (14), p.7427-7437 |
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| creator | AUWERX, Joeri STEVENS, Miguel VAN ROMPAY, An R BIRD, Louise E JINGSHAN REN DE CLERCQ, Erik ÖBERG, Bo STAMMERS, David K KARLSSON, Anna BALZARINI, Jan |
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| doi_str_mv | 10.1128/JVI.78.14.7427-7437.2004 |
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</description><identifier>ISSN: 0022-538X</identifier><identifier>EISSN: 1098-5514</identifier><identifier>DOI: 10.1128/JVI.78.14.7427-7437.2004</identifier><identifier>PMID: 15220416</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Amino Acid Sequence ; Anti-HIV Agents - pharmacology ; Biological and medical sciences ; Cells, Cultured ; Cytopathogenic Effect, Viral ; Drug Resistance, Viral ; Fundamental and applied biological sciences. Psychology ; HIV Reverse Transcriptase ; HIV-1 - drug effects ; HIV-2 - drug effects ; HIV-2 - enzymology ; HIV-2 - genetics ; Human immunodeficiency virus 2 ; Humans ; Microbial Sensitivity Tests ; Microbiology ; Miscellaneous ; Models, Molecular ; Molecular Sequence Data ; Mutation ; Reverse Transcriptase Inhibitors - pharmacology ; RNA-Directed DNA Polymerase - chemistry ; RNA-Directed DNA Polymerase - drug effects ; RNA-Directed DNA Polymerase - genetics ; Thiazoles - chemistry ; Thiazoles - pharmacology ; Triazoles - chemistry ; Triazoles - pharmacology ; Vaccines and Antiviral Agents ; Virology</subject><ispartof>Journal of Virology, 2004-07, Vol.78 (14), p.7427-7437</ispartof><rights>2004 INIST-CNRS</rights><rights>Copyright © 2004, American Society for Microbiology 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c541t-37f4b8325493ed2f467105333cc6102cd02de21fe29be964a2717c4af3ac43733</citedby><cites>FETCH-LOGICAL-c541t-37f4b8325493ed2f467105333cc6102cd02de21fe29be964a2717c4af3ac43733</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC434123/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC434123/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,550,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15923156$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15220416$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:1931513$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>AUWERX, Joeri</creatorcontrib><creatorcontrib>STEVENS, Miguel</creatorcontrib><creatorcontrib>VAN ROMPAY, An R</creatorcontrib><creatorcontrib>BIRD, Louise E</creatorcontrib><creatorcontrib>JINGSHAN REN</creatorcontrib><creatorcontrib>DE CLERCQ, Erik</creatorcontrib><creatorcontrib>ÖBERG, Bo</creatorcontrib><creatorcontrib>STAMMERS, David K</creatorcontrib><creatorcontrib>KARLSSON, Anna</creatorcontrib><creatorcontrib>BALZARINI, Jan</creatorcontrib><title>The Phenylmethylthiazolylthiourea Nonnucleoside Reverse Transcriptase (RT) Inhibitor MSK-076 Selects for a Resistance Mutation in the Active Site of Human Immunodeficiency Virus Type 2 RT</title><title>Journal of Virology</title><addtitle>J Virol</addtitle><description>Article Usage Stats
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</description><subject>Amino Acid Sequence</subject><subject>Anti-HIV Agents - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Cells, Cultured</subject><subject>Cytopathogenic Effect, Viral</subject><subject>Drug Resistance, Viral</subject><subject>Fundamental and applied biological sciences. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>15220416</pmid><doi>10.1128/JVI.78.14.7427-7437.2004</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; SWEPUB Freely available online |
| subjects | Amino Acid Sequence Anti-HIV Agents - pharmacology Biological and medical sciences Cells, Cultured Cytopathogenic Effect, Viral Drug Resistance, Viral Fundamental and applied biological sciences. Psychology HIV Reverse Transcriptase HIV-1 - drug effects HIV-2 - drug effects HIV-2 - enzymology HIV-2 - genetics Human immunodeficiency virus 2 Humans Microbial Sensitivity Tests Microbiology Miscellaneous Models, Molecular Molecular Sequence Data Mutation Reverse Transcriptase Inhibitors - pharmacology RNA-Directed DNA Polymerase - chemistry RNA-Directed DNA Polymerase - drug effects RNA-Directed DNA Polymerase - genetics Thiazoles - chemistry Thiazoles - pharmacology Triazoles - chemistry Triazoles - pharmacology Vaccines and Antiviral Agents Virology |
| title | The Phenylmethylthiazolylthiourea Nonnucleoside Reverse Transcriptase (RT) Inhibitor MSK-076 Selects for a Resistance Mutation in the Active Site of Human Immunodeficiency Virus Type 2 RT |
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