In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Increased Resistance to ABT-378, a Novel Protease Inhibitor
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Veröffentlicht in: | Journal of Virology 1998-09, Vol.72 (9), p.7532-7541 |
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creator | Carrillo, A Stewart, K D Sham, H L Norbeck, D W Kohlbrenner, W E Leonard, J M Kempf, D J Molla, A |
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</description><identifier>ISSN: 0022-538X</identifier><identifier>EISSN: 1098-5514</identifier><identifier>DOI: 10.1128/jvi.72.9.7532-7541.1998</identifier><identifier>PMID: 9696850</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>AIDS/HIV ; Amino Acid Sequence ; Animal Viruses ; Animals ; Anti-HIV Agents - chemistry ; Anti-HIV Agents - pharmacology ; Binding Sites ; Cell Line, Transformed ; COS Cells ; Drug Resistance, Microbial ; Genetic Variation ; HIV Protease - drug effects ; HIV Protease - genetics ; HIV Protease - metabolism ; HIV-1 - drug effects ; HIV-1 - enzymology ; HIV-1 - genetics ; Humans ; Lopinavir ; Molecular Sequence Data ; Molecular Structure ; Mutation ; Pyrimidinones - chemistry ; Pyrimidinones - pharmacology ; Ritonavir - pharmacology ; Saquinavir - pharmacology ; Tumor Cells, Cultured</subject><ispartof>Journal of Virology, 1998-09, Vol.72 (9), p.7532-7541</ispartof><rights>Copyright © 1998, American Society for Microbiology 1998</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c468t-b270c980edee9ad6b06464a108ca4d20542db7e654f40f7272a47beb22073e1d3</citedby><cites>FETCH-LOGICAL-c468t-b270c980edee9ad6b06464a108ca4d20542db7e654f40f7272a47beb22073e1d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC109995/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC109995/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53770,53772</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9696850$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Carrillo, A</creatorcontrib><creatorcontrib>Stewart, K D</creatorcontrib><creatorcontrib>Sham, H L</creatorcontrib><creatorcontrib>Norbeck, D W</creatorcontrib><creatorcontrib>Kohlbrenner, W E</creatorcontrib><creatorcontrib>Leonard, J M</creatorcontrib><creatorcontrib>Kempf, D J</creatorcontrib><creatorcontrib>Molla, A</creatorcontrib><title>In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Increased Resistance to ABT-378, a Novel Protease Inhibitor</title><title>Journal of Virology</title><addtitle>J Virol</addtitle><description>Article Usage Stats
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</description><subject>AIDS/HIV</subject><subject>Amino Acid Sequence</subject><subject>Animal Viruses</subject><subject>Animals</subject><subject>Anti-HIV Agents - chemistry</subject><subject>Anti-HIV Agents - pharmacology</subject><subject>Binding Sites</subject><subject>Cell Line, Transformed</subject><subject>COS Cells</subject><subject>Drug Resistance, Microbial</subject><subject>Genetic Variation</subject><subject>HIV Protease - drug effects</subject><subject>HIV Protease - genetics</subject><subject>HIV Protease - metabolism</subject><subject>HIV-1 - drug effects</subject><subject>HIV-1 - enzymology</subject><subject>HIV-1 - genetics</subject><subject>Humans</subject><subject>Lopinavir</subject><subject>Molecular Sequence Data</subject><subject>Molecular Structure</subject><subject>Mutation</subject><subject>Pyrimidinones - chemistry</subject><subject>Pyrimidinones - pharmacology</subject><subject>Ritonavir - pharmacology</subject><subject>Saquinavir - pharmacology</subject><subject>Tumor Cells, Cultured</subject><issn>0022-538X</issn><issn>1098-5514</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFksFu1DAQhiMEKtvCIyDMhRNZbMeO4wOHsqJ0UQUIlhU3y3EmjavE3trOVsuT8Lhk2VWBEydL8__fyDP_ZNlzgueE0Or1zdbOBZ3LueAFzQVnZE6krB5kM4JllXNO2MNshjGlOS-q74-z0xhvMCaMlewkO5GlLCuOZ9nPpUNrm4JHX6EHk6x3SLsGLTodtEkQ7A_9u-hbdDkO2qHlMIzON9BaY8GZ3YSHMaLVbgOIoLUOVrsU0Z1NHVo6E0BHaNAXiDYm7Qyg5NH521VeiOoV0uij30KPPgef9saJ6Gxtkw9Psket7iM8Pb5n2beLd6vFZX716f1ycX6VG1ZWKa-pwEZWGBoAqZuyxuU0oSa4Mpo1FHNGm1pAyVnLcCuooJqJGmpKsSiANMVZ9ubQdzPWAzQGXAq6V5tgBx12ymur_lWc7dS136ppz1LyiX955IO_HSEmNdhooO-1Az9GVWHMK8bFf42kZJwWBE9GcTCa4GMM0N5_hmC1D199WC-VoEqqffhqH77ahz-Rz_6e5Z47pj3pLw56Z6-7OxtA6Tio6ZT-dCt-AScNuX4</recordid><startdate>19980901</startdate><enddate>19980901</enddate><creator>Carrillo, A</creator><creator>Stewart, K D</creator><creator>Sham, H L</creator><creator>Norbeck, D W</creator><creator>Kohlbrenner, W E</creator><creator>Leonard, J M</creator><creator>Kempf, D J</creator><creator>Molla, A</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19980901</creationdate><title>In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Increased Resistance to ABT-378, a Novel Protease Inhibitor</title><author>Carrillo, A ; 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>9696850</pmid><doi>10.1128/jvi.72.9.7532-7541.1998</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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subjects | AIDS/HIV Amino Acid Sequence Animal Viruses Animals Anti-HIV Agents - chemistry Anti-HIV Agents - pharmacology Binding Sites Cell Line, Transformed COS Cells Drug Resistance, Microbial Genetic Variation HIV Protease - drug effects HIV Protease - genetics HIV Protease - metabolism HIV-1 - drug effects HIV-1 - enzymology HIV-1 - genetics Humans Lopinavir Molecular Sequence Data Molecular Structure Mutation Pyrimidinones - chemistry Pyrimidinones - pharmacology Ritonavir - pharmacology Saquinavir - pharmacology Tumor Cells, Cultured |
title | In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Increased Resistance to ABT-378, a Novel Protease Inhibitor |
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