Importance of the bovine papillomavirus P2443 promoter in the regulation of E2 and E5 expression
The full-length bovine papillomavirus E2 gene product (E2TA), which has a direct role in DNA replication and functions as a transcriptional activator, can be expressed from an unspliced mRNA transcribed from the P2443 promoter or from spliced mRNAs transcribed from other upstream promoters. The regu...
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| Veröffentlicht in: | Journal of Virology 1993-10, Vol.67 (10), p.6278-6284 |
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| container_title | Journal of Virology |
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| creator | Spalholz, B.A |
| description | The full-length bovine papillomavirus E2 gene product (E2TA), which has a direct role in DNA replication and functions as a transcriptional activator, can be expressed from an unspliced mRNA transcribed from the P2443 promoter or from spliced mRNAs transcribed from other upstream promoters. The regulation of E2 expression from these promoters is still in question. In the background of wild-type protein coding sequences, this study identified the P2443 promoter as the major source of E2TA as well as E5 expression in C127 cells |
| doi_str_mv | 10.1128/jvi.67.10.6278-6284.1993 |
| format | Article |
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| ispartof | Journal of Virology, 1993-10, Vol.67 (10), p.6278-6284 |
| issn | 0022-538X 1098-5514 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | ADN Animals ARN MENSAJERO ARN MESSAGER Base Sequence Biological and medical sciences Bovine papillomavirus 1 - genetics Bovine papillomavirus 1 - metabolism Cell Line DNA, Viral - metabolism DNA-Binding Proteins - biosynthesis EXPRESION GENICA EXPRESSION DES GENES Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Viral GENETICA Genetics GENETIQUE Mice Microbiology Molecular Sequence Data Oncogene Proteins, Viral - biosynthesis PAPILLOMAVIRUS BOVIN Promoter Regions, Genetic PROTEINAS PROTEINE RNA, Viral - biosynthesis RNA, Viral - isolation & purification Transcriptional Activation Transfection Transformation, Genetic Viral Proteins - biosynthesis Virology VIRUS DEL PAPILOMA BOVINO |
| title | Importance of the bovine papillomavirus P2443 promoter in the regulation of E2 and E5 expression |
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