Molecular Characterization of Syphilis in Patients in Canada: Azithromycin Resistance and Detection of Treponema pallidum DNA in Whole-Blood Samples versus Ulcerative Swabs

Although detection of Treponema pallidum DNA in whole-blood specimens of syphilis patients has been reported, it is uncertain at what stage of the disease such specimens are most suitable for the molecular diagnosis of syphilis. Also, few studies have directly compared the different gene targets for...

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Veröffentlicht in:	Journal of Clinical Microbiology 2009-06, Vol.47 (6), p.1668-1673
Hauptverfasser:	Martin, Irene E, Tsang, Raymond S.W, Sutherland, Karen, Tilley, Peter, Read, Ron, Anderson, Barbara, Roy, Colleen, Singh, Ameeta E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Alberta Anti-Bacterial Agents - pharmacology Azithromycin - pharmacology Bacterial diseases Bacterial diseases of the genital system Bacteriology Biological and medical sciences Blood - microbiology Child Child, Preschool DNA, Bacterial - genetics Drug Resistance, Bacterial Female Fundamental and applied biological sciences. Psychology Human bacterial diseases Humans Infant Infant, Newborn Infectious diseases Male Medical sciences Microbiology Middle Aged Miscellaneous Polymerase Chain Reaction - methods Sensitivity and Specificity Syphilis - diagnosis Syphilis - microbiology Treponema pallidum Treponema pallidum - drug effects Treponema pallidum - genetics Treponema pallidum - isolation & purification Ulcer - microbiology Young Adult
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