Different internal metabolites trigger the induction of glycolytic gene expression in Saccharomyces cerevisiae
In the yeast Saccharomyces cerevisiae, the sugar-induced expression of various genes coding for glycolytic enzymes is triggered by increases in the concentrations of different internal metabolites. Here, we show that the induction of the glycolytic isoenzyme enolase 2 is strictly dependent on the ab...
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| Veröffentlicht in: | Journal of Bacteriology 1995-08, Vol.177 (15), p.4517-4519 |
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| container_title | Journal of Bacteriology |
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| creator | Müller, S Boles, E May, M Zimmermann, F K |
| description | In the yeast Saccharomyces cerevisiae, the sugar-induced expression of various genes coding for glycolytic enzymes is triggered by increases in the concentrations of different internal metabolites. Here, we show that the induction of the glycolytic isoenzyme enolase 2 is strictly dependent on the abilities of different mutant strains to increase the level of glucose-6-phosphate after the addition of sugars. In contrast, the induction of alcohol dehydrogenase I is dependent on increasing concentrations of metabolites in the late stages of glycolysis. |
| doi_str_mv | 10.1128/jb.177.15.4517-4519.1995 |
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Here, we show that the induction of the glycolytic isoenzyme enolase 2 is strictly dependent on the abilities of different mutant strains to increase the level of glucose-6-phosphate after the addition of sugars. In contrast, the induction of alcohol dehydrogenase I is dependent on increasing concentrations of metabolites in the late stages of glycolysis.</description><identifier>ISSN: 0021-9193</identifier><identifier>EISSN: 1098-5530</identifier><identifier>EISSN: 1067-8832</identifier><identifier>DOI: 10.1128/jb.177.15.4517-4519.1995</identifier><identifier>PMID: 7635834</identifier><identifier>CODEN: JOBAAY</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>actividad enzimatica ; activite enzymatique ; alcohol dehydrogenase ; Alcohol Dehydrogenase - biosynthesis ; Alcohol Dehydrogenase - genetics ; alcohol deshidrogenasa ; alcool deshydrogenase ; Bacteriology ; Carbohydrate Metabolism ; Carbohydrates - genetics ; Enzyme Induction - genetics ; enzymic activity ; expresion genica ; expression des genes ; gene ; gene expression ; Gene Expression Regulation, Bacterial - physiology ; Gene Expression Regulation, Enzymologic - physiology ; Genes ; Genetics ; glicolisis ; Glucose - metabolism ; glycolyse ; glycolysis ; Glycolysis - genetics ; hidrolasas ; hydrolase ; hydrolases ; liasas ; lyase ; lyases ; Models, Molecular ; monosacaridos ; monosaccharide ; monosaccharides ; oligosacaridos ; oligosaccharide ; oligosaccharides ; Phosphopyruvate Hydratase - biosynthesis ; Phosphopyruvate Hydratase - genetics ; saccharomyces cerevisiae ; Saccharomyces cerevisiae - enzymology ; Saccharomyces cerevisiae - genetics ; Signal Transduction - genetics ; Sugar ; Yeast</subject><ispartof>Journal of Bacteriology, 1995-08, Vol.177 (15), p.4517-4519</ispartof><rights>Copyright American Society for Microbiology Aug 1995</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c612t-d424430f6c3aeba97b3ea55adac2dd1fe73b422d1b376fac41b5db24dbde2a483</citedby><cites>FETCH-LOGICAL-c612t-d424430f6c3aeba97b3ea55adac2dd1fe73b422d1b376fac41b5db24dbde2a483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC177205/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC177205/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7635834$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Müller, S</creatorcontrib><creatorcontrib>Boles, E</creatorcontrib><creatorcontrib>May, M</creatorcontrib><creatorcontrib>Zimmermann, F K</creatorcontrib><creatorcontrib>Institut fur Mikrobiologie, Technische Hochschule Darmstadt, Darmstadt, Germany</creatorcontrib><title>Different internal metabolites trigger the induction of glycolytic gene expression in Saccharomyces cerevisiae</title><title>Journal of Bacteriology</title><addtitle>J Bacteriol</addtitle><description>In the yeast Saccharomyces cerevisiae, the sugar-induced expression of various genes coding for glycolytic enzymes is triggered by increases in the concentrations of different internal metabolites. Here, we show that the induction of the glycolytic isoenzyme enolase 2 is strictly dependent on the abilities of different mutant strains to increase the level of glucose-6-phosphate after the addition of sugars. In contrast, the induction of alcohol dehydrogenase I is dependent on increasing concentrations of metabolites in the late stages of glycolysis.</description><subject>actividad enzimatica</subject><subject>activite enzymatique</subject><subject>alcohol dehydrogenase</subject><subject>Alcohol Dehydrogenase - biosynthesis</subject><subject>Alcohol Dehydrogenase - genetics</subject><subject>alcohol deshidrogenasa</subject><subject>alcool deshydrogenase</subject><subject>Bacteriology</subject><subject>Carbohydrate Metabolism</subject><subject>Carbohydrates - genetics</subject><subject>Enzyme Induction - genetics</subject><subject>enzymic activity</subject><subject>expresion genica</subject><subject>expression des genes</subject><subject>gene</subject><subject>gene expression</subject><subject>Gene Expression Regulation, Bacterial - physiology</subject><subject>Gene Expression Regulation, Enzymologic - physiology</subject><subject>Genes</subject><subject>Genetics</subject><subject>glicolisis</subject><subject>Glucose - metabolism</subject><subject>glycolyse</subject><subject>glycolysis</subject><subject>Glycolysis - genetics</subject><subject>hidrolasas</subject><subject>hydrolase</subject><subject>hydrolases</subject><subject>liasas</subject><subject>lyase</subject><subject>lyases</subject><subject>Models, Molecular</subject><subject>monosacaridos</subject><subject>monosaccharide</subject><subject>monosaccharides</subject><subject>oligosacaridos</subject><subject>oligosaccharide</subject><subject>oligosaccharides</subject><subject>Phosphopyruvate Hydratase - biosynthesis</subject><subject>Phosphopyruvate Hydratase - genetics</subject><subject>saccharomyces cerevisiae</subject><subject>Saccharomyces cerevisiae - enzymology</subject><subject>Saccharomyces cerevisiae - genetics</subject><subject>Signal Transduction - genetics</subject><subject>Sugar</subject><subject>Yeast</subject><issn>0021-9193</issn><issn>1098-5530</issn><issn>1067-8832</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUctu1DAUjRCoDIVPAFks2CX4GScLFqg8pUosSteWHzeJR0k82EnL_D2OZlSgm-PFPQ_fe4oCEVwRQpv3e1MRKSsiKi6ILDO0FWlb8aTYEdw2pRAMPy12GFNStqRlz4sXKe0xJpwLelFcyJqJhvFdMX_yXQcR5gX5eYE46xFNsGgTRr9AQkv0fQ8RLQNkglvt4sOMQof68WjDeFy8RT3MgOD3IUJK29TP6EZbO-gYpqPNJjYH3PnkNbwsnnV6TPDq_F4Wt18-_7z6Vl7_-Pr96uN1aWtCl9JxyjnDXW2ZBqNbaRhoIbTTljpHOpDMcEodMUzWnbacGOEM5c44oJo37LL4cPI9rGYCZ_N-UY_qEP2k41EF7dX_k9kPqg93Kl-VYpH17876GH6tkBY1-WRhHPUMYU1KSs45abagt4-I-7BuV0yKUom5yH6Z1JxINoaUInQPHyFYbX2qvdmSFRFq63ODVm19Zunrfxd5EJ4L_Js_-H649xGUTtMju0x6cyJ1OijdR5_U7U22rzFmbZPhDwC6tWI</recordid><startdate>19950801</startdate><enddate>19950801</enddate><creator>Müller, S</creator><creator>Boles, E</creator><creator>May, M</creator><creator>Zimmermann, F K</creator><general>American Society for Microbiology</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7TM</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19950801</creationdate><title>Different internal metabolites trigger the induction of glycolytic gene expression in Saccharomyces cerevisiae</title><author>Müller, S ; Boles, E ; May, M ; Zimmermann, F K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c612t-d424430f6c3aeba97b3ea55adac2dd1fe73b422d1b376fac41b5db24dbde2a483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>actividad enzimatica</topic><topic>activite enzymatique</topic><topic>alcohol dehydrogenase</topic><topic>Alcohol Dehydrogenase - biosynthesis</topic><topic>Alcohol Dehydrogenase - genetics</topic><topic>alcohol deshidrogenasa</topic><topic>alcool deshydrogenase</topic><topic>Bacteriology</topic><topic>Carbohydrate Metabolism</topic><topic>Carbohydrates - genetics</topic><topic>Enzyme Induction - genetics</topic><topic>enzymic activity</topic><topic>expresion genica</topic><topic>expression des genes</topic><topic>gene</topic><topic>gene expression</topic><topic>Gene Expression Regulation, Bacterial - physiology</topic><topic>Gene Expression Regulation, Enzymologic - physiology</topic><topic>Genes</topic><topic>Genetics</topic><topic>glicolisis</topic><topic>Glucose - metabolism</topic><topic>glycolyse</topic><topic>glycolysis</topic><topic>Glycolysis - genetics</topic><topic>hidrolasas</topic><topic>hydrolase</topic><topic>hydrolases</topic><topic>liasas</topic><topic>lyase</topic><topic>lyases</topic><topic>Models, Molecular</topic><topic>monosacaridos</topic><topic>monosaccharide</topic><topic>monosaccharides</topic><topic>oligosacaridos</topic><topic>oligosaccharide</topic><topic>oligosaccharides</topic><topic>Phosphopyruvate Hydratase - biosynthesis</topic><topic>Phosphopyruvate Hydratase - genetics</topic><topic>saccharomyces cerevisiae</topic><topic>Saccharomyces cerevisiae - enzymology</topic><topic>Saccharomyces cerevisiae - genetics</topic><topic>Signal Transduction - genetics</topic><topic>Sugar</topic><topic>Yeast</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Müller, S</creatorcontrib><creatorcontrib>Boles, E</creatorcontrib><creatorcontrib>May, M</creatorcontrib><creatorcontrib>Zimmermann, F K</creatorcontrib><creatorcontrib>Institut fur Mikrobiologie, Technische Hochschule Darmstadt, Darmstadt, Germany</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Bacteriology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Müller, S</au><au>Boles, E</au><au>May, M</au><au>Zimmermann, F K</au><aucorp>Institut fur Mikrobiologie, Technische Hochschule Darmstadt, Darmstadt, Germany</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Different internal metabolites trigger the induction of glycolytic gene expression in Saccharomyces cerevisiae</atitle><jtitle>Journal of Bacteriology</jtitle><addtitle>J Bacteriol</addtitle><date>1995-08-01</date><risdate>1995</risdate><volume>177</volume><issue>15</issue><spage>4517</spage><epage>4519</epage><pages>4517-4519</pages><issn>0021-9193</issn><eissn>1098-5530</eissn><eissn>1067-8832</eissn><coden>JOBAAY</coden><abstract>In the yeast Saccharomyces cerevisiae, the sugar-induced expression of various genes coding for glycolytic enzymes is triggered by increases in the concentrations of different internal metabolites. Here, we show that the induction of the glycolytic isoenzyme enolase 2 is strictly dependent on the abilities of different mutant strains to increase the level of glucose-6-phosphate after the addition of sugars. In contrast, the induction of alcohol dehydrogenase I is dependent on increasing concentrations of metabolites in the late stages of glycolysis.</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>7635834</pmid><doi>10.1128/jb.177.15.4517-4519.1995</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | actividad enzimatica activite enzymatique alcohol dehydrogenase Alcohol Dehydrogenase - biosynthesis Alcohol Dehydrogenase - genetics alcohol deshidrogenasa alcool deshydrogenase Bacteriology Carbohydrate Metabolism Carbohydrates - genetics Enzyme Induction - genetics enzymic activity expresion genica expression des genes gene gene expression Gene Expression Regulation, Bacterial - physiology Gene Expression Regulation, Enzymologic - physiology Genes Genetics glicolisis Glucose - metabolism glycolyse glycolysis Glycolysis - genetics hidrolasas hydrolase hydrolases liasas lyase lyases Models, Molecular monosacaridos monosaccharide monosaccharides oligosacaridos oligosaccharide oligosaccharides Phosphopyruvate Hydratase - biosynthesis Phosphopyruvate Hydratase - genetics saccharomyces cerevisiae Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Signal Transduction - genetics Sugar Yeast |
| title | Different internal metabolites trigger the induction of glycolytic gene expression in Saccharomyces cerevisiae |
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