Conidia but Not Yeast Cells of the Fungal Pathogen Histoplasma capsulatum Trigger a Type I Interferon Innate Immune Response in Murine Macrophages

Histoplasma capsulatum is the most common cause of fungal respiratory infections and can lead to progressive disseminated infections, particularly in immunocompromised patients. Infection occurs upon inhalation of the aerosolized spores, known as conidia. Once inside the host, conidia are phagocytos...

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Veröffentlicht in:Infection and Immunity 2010-09, Vol.78 (9), p.3871-3882
Hauptverfasser: Inglis, Diane O, Berkes, Charlotte A, Hocking Murray, Davina R, Sil, Anita
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Sprache:eng
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