Contribution of Vibrio parahaemolyticus Virulence Factors to Cytotoxicity, Enterotoxicity, and Lethality in Mice

Vibrio parahaemolyticus, one of the human-pathogenic vibrios, causes three major types of clinical illness: gastroenteritis, wound infections, and septicemia. Thermostable direct hemolysin (TDH) secreted by this bacterium has been considered a major virulence factor of gastroenteritis because it has...

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Veröffentlicht in:	Infection and Immunity 2010-04, Vol.78 (4), p.1772-1780
Hauptverfasser:	Hiyoshi, Hirotaka, Kodama, Toshio, Iida, Tetsuya, Honda, Takeshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Infections Bacterial Proteins - genetics Bacterial Proteins - toxicity Bacterial Toxins - toxicity Bacteriology Biological and medical sciences Cell Line Enterotoxins - toxicity Female Fundamental and applied biological sciences. Psychology Gene Knockout Techniques Hemolysin Proteins - toxicity Humans Ileum - microbiology Ileum - pathology Membrane Transport Proteins - genetics Mice Mice, Inbred C3H Microbiology Miscellaneous Rabbits Survival Analysis Vibrio Infections - microbiology Vibrio Infections - mortality Vibrio parahaemolyticus - pathogenicity Virulence Factors - toxicity
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