Ascaris suum-Derived Products Suppress Mucosal Allergic Inflammation in an Interleukin-10-Independent Manner via Interference with Dendritic Cell Function

We have previously demonstrated that protection from allergic inflammation by Ascaris suum infection was characterized by a global increase in interleukin-10 (IL-10) and the development of protective CD4⁺/CD25⁺ T cells (L. Schopf, S. Luccioli, V. Bundoc, P. Justice, C. C. Chan, B. J. Wetzel, H. H. N...

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Veröffentlicht in:	Infection and Immunity 2006-12, Vol.74 (12), p.6632-6641
Hauptverfasser:	McConchie, Brittany W, Norris, Hillary H, Bundoc, Virgilio G, Trivedi, Shweta, Boesen, Agnieszka, Urban, Joseph F. Jr, Keane-Myers, Andrea M
Format:	Artikel
Sprache:	eng
Schlagworte:	allergens Ambrosia Ambrosia - immunology Animals Antigens, Plant - immunology Ascaris suum Ascaris suum - immunology Asthma - pathology Asthma - prevention & control Biological and medical sciences body fluids Bronchoalveolar Lavage Fluid - immunology Conjunctivitis, Allergic - pathology Conjunctivitis, Allergic - prevention & control Cytokines - metabolism dendritic cells Dendritic Cells - immunology Fundamental and applied biological sciences. Psychology Fungal and Parasitic Infections hypersensitivity immunosuppression (physiological) inflammation Inflammation - prevention & control interleukin-10 Interleukin-10 - genetics Interleukin-10 - physiology Lipopolysaccharides - immunology Mice Mice, Mutant Strains Microbiology mucosa pollen pseudocoelomic fluid Pulmonary Eosinophilia - prevention & control Respiratory Hypersensitivity - pathology Respiratory Hypersensitivity - prevention & control Respiratory Mucosa - immunology Respiratory Mucosa - pathology Th2 Cells - immunology
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