Heterologous Expression Studies of Saccharomyces cerevisiae Reveal Two Distinct Trypanosomatid CaaX Protease Activities and Identify Their Potential Targets
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| Veröffentlicht in: | Eukaryotic Cell 2009-12, Vol.8 (12), p.1891-1900 |
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| container_end_page | 1900 |
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| container_issue | 12 |
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| container_title | Eukaryotic Cell |
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| creator | Mokry, David Z Manandhar, Surya P Chicola, Kristen A Santangelo, George M Schmidt, Walter K |
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| doi_str_mv | 10.1128/EC.00169-09 |
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</description><subject>Animals</subject><subject>Cell Membrane - drug effects</subject><subject>Cell Membrane - metabolism</subject><subject>DNA Mutational Analysis</subject><subject>Endopeptidases - genetics</subject><subject>Endopeptidases - metabolism</subject><subject>Genes, Mating Type, Fungal</subject><subject>Green Fluorescent Proteins - metabolism</subject><subject>GTP Phosphohydrolases - metabolism</subject><subject>HSP40 Heat-Shock Proteins - metabolism</subject><subject>Inhibitory Concentration 50</subject><subject>Phenotype</subject><subject>Protease Inhibitors - pharmacology</subject><subject>Protein Processing, Post-Translational - drug effects</subject><subject>Protein Transport - drug effects</subject><subject>Protozoan Proteins - metabolism</subject><subject>Saccharomyces cerevisiae - cytology</subject><subject>Saccharomyces cerevisiae - drug effects</subject><subject>Saccharomyces cerevisiae - genetics</subject><subject>Saccharomyces cerevisiae - metabolism</subject><subject>Saccharomyces cerevisiae Proteins - metabolism</subject><subject>Substrate Specificity - drug effects</subject><subject>Temperature</subject><subject>Trypanosoma brucei brucei - drug effects</subject><subject>Trypanosoma brucei brucei - enzymology</subject><issn>1535-9778</issn><issn>1535-9786</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkU1v1DAQhi1ERUvhxB35wgml9eTL9gWpCgutVImKbqXeLMeebAxJvLK9W_a_8GPJdqsCJ49nHj-2_BLyDtgZQC7OF80ZY1DLjMkX5ASqosokF_XL55qLY_I6xh8zVUlevCLHIEXOIIcT8vsSEwY_-JXfRLr4tQ4Yo_MTvU0b6zBS39FbbUyvgx93Zm4YDLh10Wmk33GLeqDLB08_u5jcZBJdht1aTz76USdnaaP1Pb0JPqGOSC9McluX9l49WXplcUqu29Fljy7Qm5ma93ujDitM8Q056vQQ8e3TekruviyWzWV2_e3rVXNxnZkSWMokay3XrCzbrqwF6wpAaUTLbSW04FhZaGsQreBd3lleinbuADx-Rl6XjBen5NPBu960I1ozvyLoQa2DG3XYKa-d-n8yuV6t_FblXJY5yFnw8SAwwccYsHs-C0ztQ1KLRj2GpNiefv_vdX_Zp1Rm4MMB6N2qf3ABlY6jws1Pg8OghIJcgZBQ_AGA-54x</recordid><startdate>20091201</startdate><enddate>20091201</enddate><creator>Mokry, David Z</creator><creator>Manandhar, Surya P</creator><creator>Chicola, Kristen A</creator><creator>Santangelo, George M</creator><creator>Schmidt, Walter K</creator><general>American Society for Microbiology</general><general>American Society for Microbiology (ASM)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20091201</creationdate><title>Heterologous Expression Studies of Saccharomyces cerevisiae Reveal Two Distinct Trypanosomatid CaaX Protease Activities and Identify Their Potential Targets</title><author>Mokry, David Z ; 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>19820121</pmid><doi>10.1128/EC.00169-09</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1535-9778 |
| ispartof | Eukaryotic Cell, 2009-12, Vol.8 (12), p.1891-1900 |
| issn | 1535-9778 1535-9786 |
| language | eng |
| recordid | cdi_highwire_asm_eukcell_8_12_1891 |
| source | American Society for Microbiology; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Animals Cell Membrane - drug effects Cell Membrane - metabolism DNA Mutational Analysis Endopeptidases - genetics Endopeptidases - metabolism Genes, Mating Type, Fungal Green Fluorescent Proteins - metabolism GTP Phosphohydrolases - metabolism HSP40 Heat-Shock Proteins - metabolism Inhibitory Concentration 50 Phenotype Protease Inhibitors - pharmacology Protein Processing, Post-Translational - drug effects Protein Transport - drug effects Protozoan Proteins - metabolism Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - drug effects Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Substrate Specificity - drug effects Temperature Trypanosoma brucei brucei - drug effects Trypanosoma brucei brucei - enzymology |
| title | Heterologous Expression Studies of Saccharomyces cerevisiae Reveal Two Distinct Trypanosomatid CaaX Protease Activities and Identify Their Potential Targets |
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