Replacement of a metabolic pathway for large-scale production of lactic acid from engineered yeasts

Interest in the production of L-(+)-lactic acid is presently growing in relation to its applications in the synthesis of biodegradable polymer materials. With the aim of obtaining efficient production and high productivity, we introduced the bovine L-lactate dehydrogenase gene (LDH) into a wild-type...

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Veröffentlicht in:	Applied and Environmental Microbiology 1999-09, Vol.65 (9), p.4211-4215
Hauptverfasser:	Porro, D, Bianchi, M.M, Brambilla, L, Menghini, R, Bolzani, D, Carrera, V, Lievense, J, Liu, C.L, Ranzi, B.M, Frontali, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bioreactors Biotechnology Cattle Fundamental and applied biological sciences. Psychology gene transfer Genetic Engineering Genetic technics genetic transformation Genetics and Molecular Biology Hydrogen-Ion Concentration Kluyveromyces - enzymology Kluyveromyces - genetics Kluyveromyces lactis Kluyveromyces marxianus var. lactis L-Lactate Dehydrogenase - genetics L-Lactate Dehydrogenase - metabolism Lactic acid Lactic Acid - metabolism ldh gene Metabolism Methods. Procedures. Technologies Microbiology Modification of gene expression level Plasmids Pyruvate Decarboxylase - genetics Pyruvate Decarboxylase - metabolism Transformation, Bacterial Yeast
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