Mechanism of Action of Efinaconazole, a Novel Triazole Antifungal Agent
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2013-05, Vol.57 (5), p.2405-2409 |
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creator | TATSUMI, Yoshiyuki NAGASHIMA, Maria SHIBANUSHI, Toshiyuki IWATA, Atsushi KANGAWA, Yumi INUI, Fumie SIU, William J. Jo PILLAI, Radhakrishnan NISHIYAMA, Yayoi |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.02063-12</identifier><identifier>PMID: 23459486</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>14-alpha Demethylase Inhibitors ; 14-alpha Demethylase Inhibitors - pharmacology ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antifungal Agents ; Antifungal Agents - pharmacology ; Biological and medical sciences ; Candida albicans ; Candida albicans - drug effects ; Candida albicans - growth & development ; Candida albicans - metabolism ; Candida albicans - ultrastructure ; Dose-Response Relationship, Drug ; Ergosterol - antagonists & inhibitors ; Ergosterol - biosynthesis ; Hyphae ; Hyphae - drug effects ; Hyphae - growth & development ; Hyphae - metabolism ; Hyphae - ultrastructure ; Mechanisms of Action: Physiological Effects ; Medical sciences ; Microbial Sensitivity Tests ; Microscopy, Electron, Scanning ; Pharmacology. Drug treatments ; Sterols - antagonists & inhibitors ; Sterols - biosynthesis ; Triazoles ; Triazoles - pharmacology ; Trichophyton ; Trichophyton - drug effects ; Trichophyton - growth & development ; Trichophyton - metabolism ; Trichophyton - ultrastructure ; Trichophyton mentagrophytes</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2013-05, Vol.57 (5), p.2405-2409</ispartof><rights>2014 INIST-CNRS</rights><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved.</rights><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved. 2013 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a573t-8b492fdd5bef8b2f6875877e1331932c9f0f84fd93af2e04a831a936786a8acc3</citedby><cites>FETCH-LOGICAL-a573t-8b492fdd5bef8b2f6875877e1331932c9f0f84fd93af2e04a831a936786a8acc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632939/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632939/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27275582$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23459486$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>TATSUMI, Yoshiyuki</creatorcontrib><creatorcontrib>NAGASHIMA, Maria</creatorcontrib><creatorcontrib>SHIBANUSHI, Toshiyuki</creatorcontrib><creatorcontrib>IWATA, Atsushi</creatorcontrib><creatorcontrib>KANGAWA, Yumi</creatorcontrib><creatorcontrib>INUI, Fumie</creatorcontrib><creatorcontrib>SIU, William J. Jo</creatorcontrib><creatorcontrib>PILLAI, Radhakrishnan</creatorcontrib><creatorcontrib>NISHIYAMA, Yayoi</creatorcontrib><title>Mechanism of Action of Efinaconazole, a Novel Triazole Antifungal Agent</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>14-alpha Demethylase Inhibitors</subject><subject>14-alpha Demethylase Inhibitors - pharmacology</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antifungal Agents</subject><subject>Antifungal Agents - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Candida albicans</subject><subject>Candida albicans - drug effects</subject><subject>Candida albicans - growth & development</subject><subject>Candida albicans - metabolism</subject><subject>Candida albicans - ultrastructure</subject><subject>Dose-Response Relationship, Drug</subject><subject>Ergosterol - antagonists & inhibitors</subject><subject>Ergosterol - biosynthesis</subject><subject>Hyphae</subject><subject>Hyphae - drug effects</subject><subject>Hyphae - growth & development</subject><subject>Hyphae - metabolism</subject><subject>Hyphae - ultrastructure</subject><subject>Mechanisms of Action: Physiological Effects</subject><subject>Medical sciences</subject><subject>Microbial Sensitivity Tests</subject><subject>Microscopy, Electron, Scanning</subject><subject>Pharmacology. Drug treatments</subject><subject>Sterols - antagonists & inhibitors</subject><subject>Sterols - biosynthesis</subject><subject>Triazoles</subject><subject>Triazoles - pharmacology</subject><subject>Trichophyton</subject><subject>Trichophyton - drug effects</subject><subject>Trichophyton - growth & development</subject><subject>Trichophyton - metabolism</subject><subject>Trichophyton - ultrastructure</subject><subject>Trichophyton mentagrophytes</subject><issn>0066-4804</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1ks9vFCEUx4nR2LV682zGg0lNOpXfAxeTyaZWk6qXeiZvWdilmYEKMzX2r5ftrlUPnnjwPvl-H19A6CXBZ4RQ9Q7AnmGKJWsJfYQWBGvVSqHlY7TAWMqWK8yP0LNSrnHdC42foiPKuNBcyQW6-OzsFmIoY5N809sppLirzn2IYFOEuzS40waaL-nWDc1VDvcnTR-n4Oe4gaHpNy5Oz9ETD0NxLw7rMfr24fxq-bG9_HrxadlftiA6NrVqxTX167VYOa9W1EvVCdV1jjBGNKNWe-wV92vNwFOHOShGQDPZKQkKrGXH6P1e92ZejW5tq3WGwdzkMEL-aRIE828nhq3ZpFvDJKOa6SpwchDI6fvsymTGUKwbBoguzcUQXgepM9EderpHbU6lZOcfbAg2u-xN3y_NffaG0Iq_3eNQRmqu05xjTeJ_7Ku_r_Eg_PthKvDmAECxMPgM0Ybyh-toJ4TaCb3ec9uw2f4I2ZnqbuqfMKIzwlCOBfsFDKWjrQ</recordid><startdate>20130501</startdate><enddate>20130501</enddate><creator>TATSUMI, Yoshiyuki</creator><creator>NAGASHIMA, Maria</creator><creator>SHIBANUSHI, Toshiyuki</creator><creator>IWATA, Atsushi</creator><creator>KANGAWA, Yumi</creator><creator>INUI, Fumie</creator><creator>SIU, William J. 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Antiparasitic agents</topic><topic>Antifungal Agents</topic><topic>Antifungal Agents - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Candida albicans</topic><topic>Candida albicans - drug effects</topic><topic>Candida albicans - growth & development</topic><topic>Candida albicans - metabolism</topic><topic>Candida albicans - ultrastructure</topic><topic>Dose-Response Relationship, Drug</topic><topic>Ergosterol - antagonists & inhibitors</topic><topic>Ergosterol - biosynthesis</topic><topic>Hyphae</topic><topic>Hyphae - drug effects</topic><topic>Hyphae - growth & development</topic><topic>Hyphae - metabolism</topic><topic>Hyphae - ultrastructure</topic><topic>Mechanisms of Action: Physiological Effects</topic><topic>Medical sciences</topic><topic>Microbial Sensitivity Tests</topic><topic>Microscopy, Electron, Scanning</topic><topic>Pharmacology. Drug treatments</topic><topic>Sterols - antagonists & inhibitors</topic><topic>Sterols - biosynthesis</topic><topic>Triazoles</topic><topic>Triazoles - pharmacology</topic><topic>Trichophyton</topic><topic>Trichophyton - drug effects</topic><topic>Trichophyton - growth & development</topic><topic>Trichophyton - metabolism</topic><topic>Trichophyton - ultrastructure</topic><topic>Trichophyton mentagrophytes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>TATSUMI, Yoshiyuki</creatorcontrib><creatorcontrib>NAGASHIMA, Maria</creatorcontrib><creatorcontrib>SHIBANUSHI, Toshiyuki</creatorcontrib><creatorcontrib>IWATA, Atsushi</creatorcontrib><creatorcontrib>KANGAWA, Yumi</creatorcontrib><creatorcontrib>INUI, Fumie</creatorcontrib><creatorcontrib>SIU, William J. 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Jo</au><au>PILLAI, Radhakrishnan</au><au>NISHIYAMA, Yayoi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mechanism of Action of Efinaconazole, a Novel Triazole Antifungal Agent</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>Antimicrob Agents Chemother</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2013-05-01</date><risdate>2013</risdate><volume>57</volume><issue>5</issue><spage>2405</spage><epage>2409</epage><pages>2405-2409</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>23459486</pmid><doi>10.1128/aac.02063-12</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | 14-alpha Demethylase Inhibitors 14-alpha Demethylase Inhibitors - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal Agents Antifungal Agents - pharmacology Biological and medical sciences Candida albicans Candida albicans - drug effects Candida albicans - growth & development Candida albicans - metabolism Candida albicans - ultrastructure Dose-Response Relationship, Drug Ergosterol - antagonists & inhibitors Ergosterol - biosynthesis Hyphae Hyphae - drug effects Hyphae - growth & development Hyphae - metabolism Hyphae - ultrastructure Mechanisms of Action: Physiological Effects Medical sciences Microbial Sensitivity Tests Microscopy, Electron, Scanning Pharmacology. Drug treatments Sterols - antagonists & inhibitors Sterols - biosynthesis Triazoles Triazoles - pharmacology Trichophyton Trichophyton - drug effects Trichophyton - growth & development Trichophyton - metabolism Trichophyton - ultrastructure Trichophyton mentagrophytes |
title | Mechanism of Action of Efinaconazole, a Novel Triazole Antifungal Agent |
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