Protein-Free Efavirenz Concentrations in Cerebrospinal Fluid and Blood Plasma Are Equivalent: Applying the Law of Mass Action To Predict Protein-Free Drug Concentration

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2013-03, Vol.57 (3), p.1409-1414
Hauptverfasser:	AVERY, L. B, SACKTOR, N, MCARTHUR, J. C, HENDRIX, C. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Albumin Anti-HIV Agents Anti-HIV Agents - blood Anti-HIV Agents - cerebrospinal fluid Anti-HIV Agents - pharmacokinetics Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Benzoxazines Benzoxazines - blood Benzoxazines - cerebrospinal fluid Benzoxazines - pharmacokinetics Benzoxazines - therapeutic use Biological and medical sciences HIV Infections HIV Infections - blood HIV Infections - cerebrospinal fluid HIV Infections - drug therapy HIV Infections - virology HIV-1 Human immunodeficiency virus Humans Kinetics Medical sciences Pharmacology. Drug treatments Predictive Value of Tests Protein Binding Semen - chemistry Serum Albumin Serum Albumin - metabolism
Online-Zugang:	Volltext
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