The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2012-07, Vol.56 (7), p.3544-3548 |
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creator | PELT-KOOPS, J. C. Van PETT, H. E GRAUMANS, W DER VEGTE-BOLMER, M. Van GEMERT, G. J. Van ROTTMANN, M YEUNG, B. K. S DIAGANA, T. T SAUERWEIN, R. W |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.06377-11</identifier><identifier>PMID: 22508309</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Animals ; Anopheles ; Anopheles - parasitology ; Anopheles stephensi ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antimalarials ; Antimalarials - pharmacology ; Biological and medical sciences ; Gametogenesis ; Gametogenesis - drug effects ; Indoles ; Indoles - pharmacology ; Insect Vectors ; Insect Vectors - parasitology ; Mechanisms of Action: Physiological Effects ; Medical sciences ; Pharmacology. Drug treatments ; Plasmodium falciparum ; Plasmodium falciparum - drug effects ; Plasmodium falciparum - pathogenicity ; Spiro Compounds ; Spiro Compounds - pharmacology</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3544-3548</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2012, American Society for Microbiology. All Rights Reserved.</rights><rights>Copyright © 2012, American Society for Microbiology. All Rights Reserved. 2012 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a573t-bab03eff2c1945b539e8cf9a2b1ed6df2de6c5abd1b127048d9a9d8c1f2489573</citedby><cites>FETCH-LOGICAL-a573t-bab03eff2c1945b539e8cf9a2b1ed6df2de6c5abd1b127048d9a9d8c1f2489573</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393464/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393464/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26068175$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22508309$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>PELT-KOOPS, J. C. Van</creatorcontrib><creatorcontrib>PETT, H. E</creatorcontrib><creatorcontrib>GRAUMANS, W</creatorcontrib><creatorcontrib>DER VEGTE-BOLMER, M. Van</creatorcontrib><creatorcontrib>GEMERT, G. J. Van</creatorcontrib><creatorcontrib>ROTTMANN, M</creatorcontrib><creatorcontrib>YEUNG, B. K. S</creatorcontrib><creatorcontrib>DIAGANA, T. T</creatorcontrib><creatorcontrib>SAUERWEIN, R. W</creatorcontrib><title>The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Animals</subject><subject>Anopheles</subject><subject>Anopheles - parasitology</subject><subject>Anopheles stephensi</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antimalarials</subject><subject>Antimalarials - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Gametogenesis</subject><subject>Gametogenesis - drug effects</subject><subject>Indoles</subject><subject>Indoles - pharmacology</subject><subject>Insect Vectors</subject><subject>Insect Vectors - parasitology</subject><subject>Mechanisms of Action: Physiological Effects</subject><subject>Medical sciences</subject><subject>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>22508309</pmid><doi>10.1128/aac.06377-11</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Animals Anopheles Anopheles - parasitology Anopheles stephensi Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials Antimalarials - pharmacology Biological and medical sciences Gametogenesis Gametogenesis - drug effects Indoles Indoles - pharmacology Insect Vectors Insect Vectors - parasitology Mechanisms of Action: Physiological Effects Medical sciences Pharmacology. Drug treatments Plasmodium falciparum Plasmodium falciparum - drug effects Plasmodium falciparum - pathogenicity Spiro Compounds Spiro Compounds - pharmacology |
title | The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector |
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