Determinants of Individual Variation in Intracellular Accumulation of Anti-HIV Nucleoside Analog Metabolites

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2011-02, Vol.55 (2), p.895-903
Hauptverfasser:	PAINTSIL, Elijah, DUTSCHMAN, Ginger E, RONG HU, GRILL, Susan P, WANG, Chuan-Jen, LAM, Wing, LI, Fang-Yong, GHEBREMICHAEL, Musie, NORTHRUP, Veronika, CHENG, Yung-Chi
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents Anti-HIV Agents - chemistry Anti-HIV Agents - metabolism Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Biological and medical sciences CD4-Positive T-Lymphocytes - enzymology CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Cross-Sectional Studies Deoxycytidine Kinase - metabolism Female HIV Seronegativity Human immunodeficiency virus Humans Lamivudine Lamivudine - analogs & derivatives Lamivudine - metabolism Leukocytes, Mononuclear Leukocytes, Mononuclear - enzymology Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - metabolism Lymphocyte Activation Male Medical sciences Nucleosides Nucleosides - chemistry Nucleosides - metabolism Pharmacology. Drug treatments Polyphosphates - metabolism Sex Factors Stavudine Stavudine - analogs & derivatives Stavudine - metabolism Thymidine Kinase - metabolism Treatment Outcome Zidovudine Zidovudine - analogs & derivatives Zidovudine - metabolism
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