The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2010-05, Vol.54 (5), p.1930-1940 |
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| container_issue | 5 |
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| container_title | Antimicrobial Agents and Chemotherapy |
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| creator | LOREGIAN, Arianna MERCORELLI, Beatrice CECCHETTI, Violetta PALU, Giorgio MURATORE, Giulia SINIGALIA, Elisa PAGNI, Silvana MASSARI, Serena GRIBAUDO, Giorgio GATTO, Barbara PALUMBO, Manlio TABARRINI, Oriana |
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| doi_str_mv | 10.1128/AAC.01730-09 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.01730-09</identifier><identifier>PMID: 20194695</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Aminoquinolines ; Aminoquinolines - pharmacology ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Antiviral Agents - pharmacology ; Biological and medical sciences ; Cells, Cultured ; Cytomegalovirus ; Cytomegalovirus - drug effects ; Cytomegalovirus - growth & development ; Cytomegalovirus Infections ; Cytomegalovirus Infections - drug therapy ; Cytomegalovirus Infections - virology ; DNA-Directed DNA Polymerase - metabolism ; Drug Synergism ; Fibroblasts ; Fibroblasts - cytology ; Fibroblasts - virology ; Gene Expression Regulation, Viral - drug effects ; Human cytomegalovirus ; Humans ; Immediate-Early Proteins ; Immediate-Early Proteins - metabolism ; Infectious diseases ; Medical sciences ; Pharmacology. Drug treatments ; Trans-Activators ; Trans-Activators - metabolism ; Transcription, Genetic - drug effects ; Viral diseases ; Virus Replication - drug effects</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2010-05, Vol.54 (5), p.1930-1940</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2010 American Society for Microbiology</rights><rights>Copyright © 2010, American Society for Microbiology 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a505t-3ae2a644a1c6213a39e3a33e7ae6ff4aea329bc5a5aa8a01a21893223ad5a1653</citedby><cites>FETCH-LOGICAL-a505t-3ae2a644a1c6213a39e3a33e7ae6ff4aea329bc5a5aa8a01a21893223ad5a1653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863603/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863603/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22730494$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20194695$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LOREGIAN, Arianna</creatorcontrib><creatorcontrib>MERCORELLI, Beatrice</creatorcontrib><creatorcontrib>CECCHETTI, Violetta</creatorcontrib><creatorcontrib>PALU, Giorgio</creatorcontrib><creatorcontrib>MURATORE, Giulia</creatorcontrib><creatorcontrib>SINIGALIA, Elisa</creatorcontrib><creatorcontrib>PAGNI, Silvana</creatorcontrib><creatorcontrib>MASSARI, Serena</creatorcontrib><creatorcontrib>GRIBAUDO, Giorgio</creatorcontrib><creatorcontrib>GATTO, Barbara</creatorcontrib><creatorcontrib>PALUMBO, Manlio</creatorcontrib><creatorcontrib>TABARRINI, Oriana</creatorcontrib><title>The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Aminoquinolines</subject><subject>Aminoquinolines - pharmacology</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antiviral Agents</subject><subject>Antiviral Agents - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Cells, Cultured</subject><subject>Cytomegalovirus</subject><subject>Cytomegalovirus - drug effects</subject><subject>Cytomegalovirus - growth & development</subject><subject>Cytomegalovirus Infections</subject><subject>Cytomegalovirus Infections - drug therapy</subject><subject>Cytomegalovirus Infections - virology</subject><subject>DNA-Directed DNA Polymerase - metabolism</subject><subject>Drug Synergism</subject><subject>Fibroblasts</subject><subject>Fibroblasts - cytology</subject><subject>Fibroblasts - virology</subject><subject>Gene Expression Regulation, Viral - drug effects</subject><subject>Human cytomegalovirus</subject><subject>Humans</subject><subject>Immediate-Early Proteins</subject><subject>Immediate-Early Proteins - metabolism</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Pharmacology. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Antiviral Agents</topic><topic>Antiviral Agents - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Cells, Cultured</topic><topic>Cytomegalovirus</topic><topic>Cytomegalovirus - drug effects</topic><topic>Cytomegalovirus - growth & development</topic><topic>Cytomegalovirus Infections</topic><topic>Cytomegalovirus Infections - drug therapy</topic><topic>Cytomegalovirus Infections - virology</topic><topic>DNA-Directed DNA Polymerase - metabolism</topic><topic>Drug Synergism</topic><topic>Fibroblasts</topic><topic>Fibroblasts - cytology</topic><topic>Fibroblasts - virology</topic><topic>Gene Expression Regulation, Viral - drug effects</topic><topic>Human cytomegalovirus</topic><topic>Humans</topic><topic>Immediate-Early Proteins</topic><topic>Immediate-Early Proteins - metabolism</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>20194695</pmid><doi>10.1128/AAC.01730-09</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 2010-05, Vol.54 (5), p.1930-1940 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_highwire_asm_aac_54_5_1930 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Aminoquinolines Aminoquinolines - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - pharmacology Biological and medical sciences Cells, Cultured Cytomegalovirus Cytomegalovirus - drug effects Cytomegalovirus - growth & development Cytomegalovirus Infections Cytomegalovirus Infections - drug therapy Cytomegalovirus Infections - virology DNA-Directed DNA Polymerase - metabolism Drug Synergism Fibroblasts Fibroblasts - cytology Fibroblasts - virology Gene Expression Regulation, Viral - drug effects Human cytomegalovirus Humans Immediate-Early Proteins Immediate-Early Proteins - metabolism Infectious diseases Medical sciences Pharmacology. Drug treatments Trans-Activators Trans-Activators - metabolism Transcription, Genetic - drug effects Viral diseases Virus Replication - drug effects |
| title | The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein |
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