Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2004-04, Vol.48 (4), p.1175-1187 |
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creator | Bagge, Niels Schuster, Martin Hentzer, Morten Ciofu, Oana Givskov, Michael Greenberg, Everett Peter Høiby, Niels |
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doi_str_mv | 10.1128/AAC.48.4.1175-1187.2004 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.48.4.1175-1187.2004</identifier><identifier>PMID: 15047518</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Alginates ; Alginates - metabolism ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Bacterial Proteins - biosynthesis ; Bacterial Proteins - genetics ; beta-Lactamases ; beta-Lactamases - biosynthesis ; beta-Lactamases - genetics ; Biofilms ; Biofilms - drug effects ; Biological and medical sciences ; Dose-Response Relationship, Drug ; Gene Expression Regulation, Bacterial ; Gene Expression Regulation, Bacterial - drug effects ; Genes, Bacterial - genetics ; Image Processing, Computer-Assisted ; Imipenem ; Imipenem - pharmacology ; Mechanisms of Action: Physiological Effects ; Medical sciences ; N-Acetylmuramoyl-L-alanine Amidase - biosynthesis ; N-Acetylmuramoyl-L-alanine Amidase - genetics ; Oligonucleotide Array Sequence Analysis ; Pharmacology. Drug treatments ; Polysaccharides - analysis ; Polysaccharides - biosynthesis ; Protein Folding ; Pseudomonas aeruginosa ; Pseudomonas aeruginosa - drug effects ; Pseudomonas aeruginosa - enzymology ; Pseudomonas aeruginosa - genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Thienamycins ; Thienamycins - pharmacology ; Transcription, Genetic - drug effects</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2004-04, Vol.48 (4), p.1175-1187</ispartof><rights>2004 INIST-CNRS</rights><rights>Copyright © 2004 American Society for Microbiology</rights><rights>Copyright © 2004, American Society for Microbiology 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a544t-2ed805c859f462a4e9049600a64a185a04378c18a7089850a20931cedccf13623</citedby><cites>FETCH-LOGICAL-a544t-2ed805c859f462a4e9049600a64a185a04378c18a7089850a20931cedccf13623</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC375275/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC375275/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15610241$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15047518$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bagge, Niels</creatorcontrib><creatorcontrib>Schuster, Martin</creatorcontrib><creatorcontrib>Hentzer, Morten</creatorcontrib><creatorcontrib>Ciofu, Oana</creatorcontrib><creatorcontrib>Givskov, Michael</creatorcontrib><creatorcontrib>Greenberg, Everett Peter</creatorcontrib><creatorcontrib>Høiby, Niels</creatorcontrib><title>Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Alginates</subject><subject>Alginates - metabolism</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Bacterial Proteins - biosynthesis</subject><subject>Bacterial Proteins - genetics</subject><subject>beta-Lactamases</subject><subject>beta-Lactamases - biosynthesis</subject><subject>beta-Lactamases - genetics</subject><subject>Biofilms</subject><subject>Biofilms - drug effects</subject><subject>Biological and medical sciences</subject><subject>Dose-Response Relationship, Drug</subject><subject>Gene Expression Regulation, Bacterial</subject><subject>Gene Expression Regulation, Bacterial - drug effects</subject><subject>Genes, Bacterial - genetics</subject><subject>Image Processing, Computer-Assisted</subject><subject>Imipenem</subject><subject>Imipenem - pharmacology</subject><subject>Mechanisms of Action: Physiological Effects</subject><subject>Medical sciences</subject><subject>N-Acetylmuramoyl-L-alanine Amidase - biosynthesis</subject><subject>N-Acetylmuramoyl-L-alanine Amidase - genetics</subject><subject>Oligonucleotide Array Sequence Analysis</subject><subject>Pharmacology. Drug treatments</subject><subject>Polysaccharides - analysis</subject><subject>Polysaccharides - biosynthesis</subject><subject>Protein Folding</subject><subject>Pseudomonas aeruginosa</subject><subject>Pseudomonas aeruginosa - drug effects</subject><subject>Pseudomonas aeruginosa - enzymology</subject><subject>Pseudomonas aeruginosa - genetics</subject><subject>Reverse Transcriptase Polymerase Chain Reaction</subject><subject>Thienamycins</subject><subject>Thienamycins - pharmacology</subject><subject>Transcription, Genetic - drug effects</subject><issn>0066-4804</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcGO0zAQhi0EYkvhFcAc4JYyTuzEOXAo1VJWqsQe4GxNHafxKrGLnSzwAjwQD8Iz4dCKXW5IlqyZ-X7_tn9CXjBYMZbLN-v1ZsXliqeqEhljslrlAPwBWTCoZVaKunxIFgBlmXEJ_II8ifEGUi1qeEwumABeCSYX5Md1NFPjB-8wUjRhOljnI9J31re2HyK9_Hb00TR09PRqsEfjzJB6nd3bkW46dAcTqXV02_s99nSb5rMkmBitdxRdQ3_9zHaoRxwwmj-NdZ9McDT0Ovhm0mMCn5JHLfbRPDvvS_L5_eWnzYds93F7tVnvMhScj1luGglCS1G3vMyRmxp4XQJgyZFJgcCLSmomsQJZSwGYQ10wbRqtW1aUebEkb0_nHqf9kNrGjQF7dQx2wPBdebTq34mznTr4W1VUIq9E0r8-64P_Mpk4qsFGbfoenfFTVExCwYu0lqQ6gTr4GINp_3owUHOEKkWouFRczRGqOUI1R5iU_KTEOOTqxk_BpR_5D9nz-y-7sztHnYBXZwCjxr4N6LSN97iSQc5Z4l6euM4euq82GJUuohD1nW3xGzUpwaI</recordid><startdate>20040401</startdate><enddate>20040401</enddate><creator>Bagge, Niels</creator><creator>Schuster, Martin</creator><creator>Hentzer, Morten</creator><creator>Ciofu, Oana</creator><creator>Givskov, Michael</creator><creator>Greenberg, Everett Peter</creator><creator>Høiby, Niels</creator><general>American Society for Microbiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>5PM</scope></search><sort><creationdate>20040401</creationdate><title>Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production</title><author>Bagge, Niels ; Schuster, Martin ; Hentzer, Morten ; Ciofu, Oana ; Givskov, Michael ; Greenberg, Everett Peter ; Høiby, Niels</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a544t-2ed805c859f462a4e9049600a64a185a04378c18a7089850a20931cedccf13623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Alginates</topic><topic>Alginates - metabolism</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Bacterial Proteins - biosynthesis</topic><topic>Bacterial Proteins - genetics</topic><topic>beta-Lactamases</topic><topic>beta-Lactamases - biosynthesis</topic><topic>beta-Lactamases - genetics</topic><topic>Biofilms</topic><topic>Biofilms - drug effects</topic><topic>Biological and medical sciences</topic><topic>Dose-Response Relationship, Drug</topic><topic>Gene Expression Regulation, Bacterial</topic><topic>Gene Expression Regulation, Bacterial - drug effects</topic><topic>Genes, Bacterial - genetics</topic><topic>Image Processing, Computer-Assisted</topic><topic>Imipenem</topic><topic>Imipenem - pharmacology</topic><topic>Mechanisms of Action: Physiological Effects</topic><topic>Medical sciences</topic><topic>N-Acetylmuramoyl-L-alanine Amidase - biosynthesis</topic><topic>N-Acetylmuramoyl-L-alanine Amidase - genetics</topic><topic>Oligonucleotide Array Sequence Analysis</topic><topic>Pharmacology. Drug treatments</topic><topic>Polysaccharides - analysis</topic><topic>Polysaccharides - biosynthesis</topic><topic>Protein Folding</topic><topic>Pseudomonas aeruginosa</topic><topic>Pseudomonas aeruginosa - drug effects</topic><topic>Pseudomonas aeruginosa - enzymology</topic><topic>Pseudomonas aeruginosa - genetics</topic><topic>Reverse Transcriptase Polymerase Chain Reaction</topic><topic>Thienamycins</topic><topic>Thienamycins - pharmacology</topic><topic>Transcription, Genetic - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bagge, Niels</creatorcontrib><creatorcontrib>Schuster, Martin</creatorcontrib><creatorcontrib>Hentzer, Morten</creatorcontrib><creatorcontrib>Ciofu, Oana</creatorcontrib><creatorcontrib>Givskov, Michael</creatorcontrib><creatorcontrib>Greenberg, Everett Peter</creatorcontrib><creatorcontrib>Høiby, Niels</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Antimicrobial Agents and Chemotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bagge, Niels</au><au>Schuster, Martin</au><au>Hentzer, Morten</au><au>Ciofu, Oana</au><au>Givskov, Michael</au><au>Greenberg, Everett Peter</au><au>Høiby, Niels</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>AAC</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2004-04-01</date><risdate>2004</risdate><volume>48</volume><issue>4</issue><spage>1175</spage><epage>1187</epage><pages>1175-1187</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>15047518</pmid><doi>10.1128/AAC.48.4.1175-1187.2004</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Alginates Alginates - metabolism Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial Proteins - biosynthesis Bacterial Proteins - genetics beta-Lactamases beta-Lactamases - biosynthesis beta-Lactamases - genetics Biofilms Biofilms - drug effects Biological and medical sciences Dose-Response Relationship, Drug Gene Expression Regulation, Bacterial Gene Expression Regulation, Bacterial - drug effects Genes, Bacterial - genetics Image Processing, Computer-Assisted Imipenem Imipenem - pharmacology Mechanisms of Action: Physiological Effects Medical sciences N-Acetylmuramoyl-L-alanine Amidase - biosynthesis N-Acetylmuramoyl-L-alanine Amidase - genetics Oligonucleotide Array Sequence Analysis Pharmacology. Drug treatments Polysaccharides - analysis Polysaccharides - biosynthesis Protein Folding Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - enzymology Pseudomonas aeruginosa - genetics Reverse Transcriptase Polymerase Chain Reaction Thienamycins Thienamycins - pharmacology Transcription, Genetic - drug effects |
title | Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production |
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