Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2001-04, Vol.45 (4), p.1192-1200 |
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creator | MAGA, Giovanni HÜBSCHER, Ulrich PREGNOLATO, Massimo UBIALI, Daniela GOSSELIN, Gilles SPADARI, Silvio |
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doi_str_mv | 10.1128/AAC.45.4.1192-1200.2001 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.45.4.1192-1200.2001</identifier><identifier>PMID: 11257034</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Anti-HIV Agents ; Anti-HIV Agents - pharmacology ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Benzoxazines ; Biological and medical sciences ; dideoxynucleoside triphosphate ; Dideoxynucleosides ; Dideoxynucleosides - pharmacology ; Dideoxynucleotides ; DNA Replication - drug effects ; DNA, Viral - drug effects ; Dose-Response Relationship, Drug ; Drug Resistance, Microbial ; Drug Synergism ; HIV Reverse Transcriptase ; HIV Reverse Transcriptase - antagonists & inhibitors ; HIV Reverse Transcriptase - genetics ; Human immunodeficiency virus 1 ; Humans ; Inhibitory Concentration 50 ; Medical sciences ; Mutation ; Nevirapine - pharmacology ; nucleoside analogs ; nucleoside analogues ; Oxazines - pharmacology ; Pharmacology. Drug treatments ; Reverse Transcriptase Inhibitors ; Reverse Transcriptase Inhibitors - pharmacology ; RNA-directed DNA polymerase inhibitors (non-nucleoside) ; Stereoisomerism ; Thymine Nucleotides - pharmacology ; Zidovudine - analogs & derivatives ; Zidovudine - pharmacology</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2001-04, Vol.45 (4), p.1192-1200</ispartof><rights>2001 INIST-CNRS</rights><rights>Copyright © 2001 American Society for Microbiology</rights><rights>Copyright © 2001, American Society for Microbiology 2001</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a492t-47dd666ee842cc1c5c3774a02655c6422e5249c0383b2c8394c82d001990beb13</citedby><cites>FETCH-LOGICAL-a492t-47dd666ee842cc1c5c3774a02655c6422e5249c0383b2c8394c82d001990beb13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC90443/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC90443/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=952522$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11257034$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MAGA, Giovanni</creatorcontrib><creatorcontrib>HÜBSCHER, Ulrich</creatorcontrib><creatorcontrib>PREGNOLATO, Massimo</creatorcontrib><creatorcontrib>UBIALI, Daniela</creatorcontrib><creatorcontrib>GOSSELIN, Gilles</creatorcontrib><creatorcontrib>SPADARI, Silvio</creatorcontrib><title>Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob. Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Anti-HIV Agents</subject><subject>Anti-HIV Agents - pharmacology</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antiviral Agents</subject><subject>Benzoxazines</subject><subject>Biological and medical sciences</subject><subject>dideoxynucleoside triphosphate</subject><subject>Dideoxynucleosides</subject><subject>Dideoxynucleosides - pharmacology</subject><subject>Dideoxynucleotides</subject><subject>DNA Replication - drug effects</subject><subject>DNA, Viral - drug effects</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Resistance, Microbial</subject><subject>Drug Synergism</subject><subject>HIV Reverse Transcriptase</subject><subject>HIV Reverse Transcriptase - antagonists & inhibitors</subject><subject>HIV Reverse Transcriptase - genetics</subject><subject>Human immunodeficiency virus 1</subject><subject>Humans</subject><subject>Inhibitory Concentration 50</subject><subject>Medical sciences</subject><subject>Mutation</subject><subject>Nevirapine - pharmacology</subject><subject>nucleoside analogs</subject><subject>nucleoside analogues</subject><subject>Oxazines - pharmacology</subject><subject>Pharmacology. Drug treatments</subject><subject>Reverse Transcriptase Inhibitors</subject><subject>Reverse Transcriptase Inhibitors - pharmacology</subject><subject>RNA-directed DNA polymerase inhibitors (non-nucleoside)</subject><subject>Stereoisomerism</subject><subject>Thymine Nucleotides - pharmacology</subject><subject>Zidovudine - analogs & derivatives</subject><subject>Zidovudine - pharmacology</subject><issn>0066-4804</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNksmO1DAQhiMEYoaBVwAjJASHNLZjZ5Hm0mqWaWlYhBo4Wo5T3fEosRtXMtCvxYNw4IlwL7Nw42BZJX9__Xb5T5InjE4Y4-Wr6XQ2EXIiYlXxlHFKJ3GxO8kxo1WZ5rLK7ybHlOZ5KkoqjpIHiBc01rKi95Oj2EMWNBPHyZ9PfgA3WD1Y74hfkrlrbW2vqm-2a9LFZg1Eu4a8HwftBnI29tqRed-PzjewtMaCMxvy1YYRyQ5m5DNcQkAgi6AdmmDXg0ZAUm_IzPe1dTs_3Fp88M6NpgOPtoErex9w59iku61LX_z-9TJ9HQn_c3MLX8TOrcd1qwcgU6c7v8KHyb2l7hAeHfaT5MvbN4vZWXr-8d18Nj1Ptaj4kIqiafI8BygFN4YZabKiEJryXEqTC85BclEZmpVZzU2ZVcKUvIlDripaQ82yk-R033c91j00Jo4x6E6tg-112Civrfr3xNlWrfylqqgQWZQ_P8iD_z4CDqq3aKDrtAM_omJFWRZC5BEs9qAJHjHA8tqCUbVNg4ppUEIqobZpUNs0qG0aolLslRp7ri78GOKE8D9kj28_7MbukJoIPDsAGo3ulvGPjcVrrpJcch6pp3uqtav2hw2g4jWU1ubGNPsL9nPdVg</recordid><startdate>20010401</startdate><enddate>20010401</enddate><creator>MAGA, Giovanni</creator><creator>HÜBSCHER, Ulrich</creator><creator>PREGNOLATO, Massimo</creator><creator>UBIALI, Daniela</creator><creator>GOSSELIN, Gilles</creator><creator>SPADARI, Silvio</creator><general>American Society for Microbiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7U9</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>5PM</scope></search><sort><creationdate>20010401</creationdate><title>Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs</title><author>MAGA, Giovanni ; HÜBSCHER, Ulrich ; PREGNOLATO, Massimo ; UBIALI, Daniela ; GOSSELIN, Gilles ; SPADARI, Silvio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a492t-47dd666ee842cc1c5c3774a02655c6422e5249c0383b2c8394c82d001990beb13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Anti-HIV Agents</topic><topic>Anti-HIV Agents - pharmacology</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Antiviral Agents</topic><topic>Benzoxazines</topic><topic>Biological and medical sciences</topic><topic>dideoxynucleoside triphosphate</topic><topic>Dideoxynucleosides</topic><topic>Dideoxynucleosides - pharmacology</topic><topic>Dideoxynucleotides</topic><topic>DNA Replication - drug effects</topic><topic>DNA, Viral - drug effects</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drug Resistance, Microbial</topic><topic>Drug Synergism</topic><topic>HIV Reverse Transcriptase</topic><topic>HIV Reverse Transcriptase - antagonists & inhibitors</topic><topic>HIV Reverse Transcriptase - genetics</topic><topic>Human immunodeficiency virus 1</topic><topic>Humans</topic><topic>Inhibitory Concentration 50</topic><topic>Medical sciences</topic><topic>Mutation</topic><topic>Nevirapine - pharmacology</topic><topic>nucleoside analogs</topic><topic>nucleoside analogues</topic><topic>Oxazines - pharmacology</topic><topic>Pharmacology. Drug treatments</topic><topic>Reverse Transcriptase Inhibitors</topic><topic>Reverse Transcriptase Inhibitors - pharmacology</topic><topic>RNA-directed DNA polymerase inhibitors (non-nucleoside)</topic><topic>Stereoisomerism</topic><topic>Thymine Nucleotides - pharmacology</topic><topic>Zidovudine - analogs & derivatives</topic><topic>Zidovudine - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MAGA, Giovanni</creatorcontrib><creatorcontrib>HÜBSCHER, Ulrich</creatorcontrib><creatorcontrib>PREGNOLATO, Massimo</creatorcontrib><creatorcontrib>UBIALI, Daniela</creatorcontrib><creatorcontrib>GOSSELIN, Gilles</creatorcontrib><creatorcontrib>SPADARI, Silvio</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Antimicrobial Agents and Chemotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MAGA, Giovanni</au><au>HÜBSCHER, Ulrich</au><au>PREGNOLATO, Massimo</au><au>UBIALI, Daniela</au><au>GOSSELIN, Gilles</au><au>SPADARI, Silvio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>Antimicrob. Agents Chemother</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2001-04-01</date><risdate>2001</risdate><volume>45</volume><issue>4</issue><spage>1192</spage><epage>1200</epage><pages>1192-1200</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>11257034</pmid><doi>10.1128/AAC.45.4.1192-1200.2001</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Anti-HIV Agents Anti-HIV Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Benzoxazines Biological and medical sciences dideoxynucleoside triphosphate Dideoxynucleosides Dideoxynucleosides - pharmacology Dideoxynucleotides DNA Replication - drug effects DNA, Viral - drug effects Dose-Response Relationship, Drug Drug Resistance, Microbial Drug Synergism HIV Reverse Transcriptase HIV Reverse Transcriptase - antagonists & inhibitors HIV Reverse Transcriptase - genetics Human immunodeficiency virus 1 Humans Inhibitory Concentration 50 Medical sciences Mutation Nevirapine - pharmacology nucleoside analogs nucleoside analogues Oxazines - pharmacology Pharmacology. Drug treatments Reverse Transcriptase Inhibitors Reverse Transcriptase Inhibitors - pharmacology RNA-directed DNA polymerase inhibitors (non-nucleoside) Stereoisomerism Thymine Nucleotides - pharmacology Zidovudine - analogs & derivatives Zidovudine - pharmacology |
title | Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs |
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