Pharmacokinetics of [14C]Abacavir, a Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Inhibitor, Administered in a Single Oral Dose to HIV-1-Infected Adults: a Mass Balance Study

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 1999-12, Vol.43 (12), p.2855-2861
Hauptverfasser:	MCDOWELL, J. A, CHITTICK, G. E, RAVITCH, J. R, POLK, R. E, KERKERING, T. M, STEIN, D. S
Format:	Artikel
Sprache:	eng
Schlagworte:	5'-Carboxylate 5'-Glucuronide Abacavir Adult Anti-HIV Agents Anti-HIV Agents - administration & dosage Anti-HIV Agents - cerebrospinal fluid Anti-HIV Agents - pharmacokinetics Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Biological and medical sciences Chromatography, High Pressure Liquid Dideoxynucleosides Dideoxynucleosides - administration & dosage Dideoxynucleosides - cerebrospinal fluid Dideoxynucleosides - pharmacokinetics Feces - chemistry HIV Infections HIV Infections - metabolism HIV Reverse Transcriptase HIV Reverse Transcriptase - antagonists & inhibitors HIV-1 Human immunodeficiency virus 1 Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments Reverse Transcriptase Inhibitors Reverse Transcriptase Inhibitors - administration & dosage Reverse Transcriptase Inhibitors - cerebrospinal fluid Reverse Transcriptase Inhibitors - pharmacokinetics Spectrophotometry, Ultraviolet
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